Haryana is northern state ofIndia with power of rural population (65.12 percent) that relies on agriculture and domestic animals for its economy and social welfare (Singh and Pal, 2018).It has hot semi-arid type climatewith average temperature of 24.9° Cand annualrainfall 653 mm (en.climatedata.org.). Main cultivated crops of study area are cotton, mustard, millet, vegetables, legumes etc. Methods: A field study was completed in January 2020 in two villages i.e. Parbhuwala and Budhakhera ofTehsil-Uklana Mandi of districtHisar. Ethnomedicinal information such as vernacular name, therapeutic uses, plant part used, herbal formulation, mode of application has been collected using a well-structured proforma. Findings: The study led to documentation of 9 plant species belonging to Euphorbiaceae family being used to treat 26 human ailments. Leaves were most dominantly used plant partfor all reported species. From collected reports it has been concluded that euphorbiaceous plants are widely used to treat skin ailments and gastrointestinal disorders.