Neurodevelopmental Impairment of Neonatal Meningitis in Full-Term and Near-Term Newborns : A Retrospective Study of One Center
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Neonates are at more serious hazard for sepsis and meningitis thandifferentages. EarlyNeonatalmeningitis due to streptococcus group B isserious but uncommondisease. The prevalence of neonatalmeningitisisestimated 0.15- 0.5per 1000 birth in industrialized countries and mortalityfromneonatalmeningitis ranges from 10–15%. Increasingntrapartumantibioticprophylaxis(IAP)coveragew aslinearlyassociatedwithdecreasedrisk of Early-onset group B streptococcaldisease (EOGBS) diseaseby 85-90%. But group B Streptococcus (GBS ; Streptococcus agalactiae) still a leadinginfectious cause of neonatalmorbidity and mortality of neonatalonsetsepsis and. Theriskwithoutan IAPpolicyisestimated 1,1%. Neurologic complications remainshigh in neonate patient withneonatalmeingitis due to streptococcus. Global eatiology of bacterialmeningitis: The occurrence of intrusive GBS illness in newbornchildrenwas 0.49 per 1000 live birth (95% certain stretch [CI], .43-.56), and wasmostelevated in Africa (1.12) and least in Asia (0.30). Early-onsetdisease incidence wasp 0.41 (95% CI, .36-.47); latte-onsetdisease incidence wasp 0.26 (95% CI, .21-.30). C. Stéréotype III (61.5%) commande, witz 97% of cases borough about by serotypesIa, Ibb, II, III, and V. Objective The aima of thisstudywas to détermine complications and neurodevelopmentalimpairement ofneonatalmeningitis, due to streptococcus group B in full and full Termnewborns in a tertiaire-levelneonate intensive care unit. Study design Twenty five (25) cases of neonatalmeningitis B streptococcus Benwee 1985 and 2010 have been reporte. Twowereexcludedbecausetheyhadcongenitalabnomalies. 14 records have not been found in the archives.