Rakamokshyana (Bloodletting) is an ancient procedure that was utilized in Ayurveda in the setting of a humoral and pathological concept as a general treatment for all ailments, as well as during the middle ages primarily as a remedy for the treatment of inflammatory and infectious diseases by other traditional medicines of world. The general population was convinced of the efficacy of this treatment for centuries, even requesting it on occasion on a prophylactic basis. Leech has been used from ancient days in Grace, Roma and Arabian countries. Susruta (1000 BC) and Charak (600-200 BC) are two sages from India to describe about leech therapy whereas western literature mentioned about Themison (80-40 BC) – a pupil of Asclepiads is the first person to describe about leech therapy