In contrast to its role as poison, hydrogen sulfide (H2S) is now considered as the thirdgaso transmitter after nitric oxide (NO) and carbon monoxide (CO) [1,2,3]. Thoughit was first reported in 1982 that they are produced in mammalian tissues, but it isonly now emerged as a mediator of important physiologic functions in humans [4].In the central nervous system (CNS), H2S functions not only as a neuro-modulator,but also as a neuro-protectant against oxidative stress