Chitosan in Medicine-A Mini Review
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hitosan is a polysaccharide made up of deacetylated β-(1-4) D-glucosamine and acetylated units of N-acetyl-D-glucosamine. Generally, chitosan is synthesized by de acetylating chitin using excess sodium hydroxide as reagent and water as solvent. Chitin can be obtained from the exoskeletons of shell mollusks, crustaceans and few species of fungal cell walls as they contain chitin in them. Chitin is one of the most abundant natural poly amino saccharide next to cellulose. Chitosan is being used commercially in seed treatment and as biopesticides for protecting against fungal infections. It is used as a fining agent in wine making process and also in storage of wine and other alcohols [1]. Chitosan is also used in enhancing tensile strength of biopolymers which are being used widely replacing synthetic hydrocarbon polymers [2,3]. Some researches proved it is useful in bioremediation process to remove heavy metals and dyes from environment [4]. Removal of pharmaceutical traces from water bodies using chitosan is also being considered by the researchers [5]. Ðe use of chitosan for immobilizing the biomolecules is being studied extensively [6]. Despite of its bio compatible properties its approval for human use is still pending by FDA. Only few countries like Japan and Korea had proposed the use of chitosan in potable water. Chitosan had become one of the primary targets in drug delivery research as almost all the countries are working to obtain globally acceptable criteria for human medical use [7].