A transdermal patch is a medicated adhesive patch that is placed at the skin to deliver a specific dose of medication via the skin and into the bloodstream. Often, this promotes restoration to an injured area of the body. An advantage of a transdermal drug delivery direction over different types of medication transport such as oral, topical, intravenous, intramuscular, etc. is that the patch affords a managed release of the medication into the patient, usually via both a porous membrane covering a reservoir of drugs or via body heat melting thin layers of medication embedded in the adhesive[1]. Transdermal drug transport gives controlled release of the drug into the patient, it allows a steady blood level profile, resulting in reduced systemic side effects and, sometimes, progressed efficacy over other dosage forms [2]. The major goal of transdermal drug transport machine is to deliver drugs into systemic circulate via pores and skin at predetermined rate with minimal inter and intrapatient variations.

The transdermal drug delivery system is a technique that provides drug absorption via the skin [3]. The system has many advantages over conventional management routes such as intravenous or oral management for systemic and local drug delivery with easy administration. It is available outdoor clinical institutions, which decreases the burden on patients because of intravenous management and reduces loss from the first pass impact of the liver [4], turning in therapeutic drugs at a controlled ratio.